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Graz离体组织浴槽系统的简单介绍
HSE—HA生理学系统是一系列应用广泛的完备产品,可用于整体动物生理学、立体或在体器官和组织灌注及组织浴槽研究。这些系统具有广泛的应用,包括传统的安全药理学、DMPK、毒理学、呼吸系统、心脏病学、分子生物学和生理学。每个系统都设计了标准的组件,再加一些其他配置以适合特殊研究的需要。。标注组惨馕蹲湃绻闶切枰钟猩璞概淦耄蛘呓邢低成叮蛘呤峭暾呐涮撞罚愣贾恍枰郝蛐枰墓辜?/SPAN>HSE-HA生理学系统为你提供各种工具,使你的研究走向多产和成功。
我们提供大多数生理学检测设备,包括放大器、电极、传感器和电化学检测器。参数包括力、位移、压力、液体和气体流、心电图(单导联—12导统)、MAP(单个或多个部位)、脑电图、*、连续支流灌注传统的血气参数和电解质的分析,可以选择程序化软件和传统的刺激器作为放大器、电极和传感器等产品的补充。
HSE-DAQ系统产品家族(BDAS、ACAD、HAEMODYN、ISOHEART、PULMODYN、PENNOCK)可以记录你的初始信号,计算到处的参数,注释数据,快速简易的输入确定的数据用于分析。同时还可以选择用于进一步分析的软件模块,带状记录纸打印,自动和控制模块等。产品经过预先设置,打开包装即可使用,并专门设计符合你的系统配置和数据分析要求。
• Designed for vascular rings but suitable for most standard pharmacological experiments
• Permits experiments both on smooth muscle, cardiac (atria), or skeletal muscles preparations
• Clear, 4-channel arrangement
• Rigid construction
• Contractions can be measured isometrically or isotonically
• Interchangeable tissue vessels: 2, 5, 10 or 20 ml
• Experiments with minimum test substance quantities are possible using small tissue vessels
• Adaptable to different tissue preparations by suitable form of tissue supports
• Tissue holders with integral field stimulating electrode available
• Simple to operate, easy to clean
The Graz Organ Bath can be used for many standard pharmacological experiments. This apparatus was developed for experiments on small isolated vascular rings (1 to 2 mm dia.) with special attention to a low incubation volume of the medium. The smallest tissue vessel available has a volume of 2 ml. The muscle contractions produced in these experiments can be measured either as forces (isometrically) or as displacements (isotonically).
The organ bath is also available in variable versions. Larger tissue vessels of 5, 10 or 20 ml are available for larger vessels and other muscle preparations. These baths can also be used for experiments on papillary muscle or isolated atria (e.g. guinea-pig), with provision for electrical stimulation. The F-30 isometric transducer that we recommend (See page I4) can easily be replaced by different transducers without any modification of the apparatus.
The main consideration in designing the bath has been a simple and clear arrangement, without neglecting the necessary stability. A rigid construction is an essential requirement for measuring small contraction forces. A rigid Plexiglas baseplate carriers 4 vertical rods on which the individual components are mounted. Tissue vessels and suitable holders are available in 4 different sizes. The perfusion solution is aerated by glass frits fused into the vessel bottom. A needle valves is provided for each tissue vessel to permit accurate adjustment of the gas flow.